The 3rd Edition of the Addiction World Conference, held from September 5 to 7, 2025, in Boston, Massachusetts, USA, served as a vibrant forum for showcasing revolutionary developments and groundbreaking research in the field of addiction. The event fostered thought-provoking discussions and interdisciplinary collaboration, with a strong emphasis on identifying emerging trends and innovative approaches that are shaping the future of addiction science, treatment strategies, prevention efforts, and recovery support systems.